The Single and Dual Epithelial Voltage Clamp Systems are designed to be used with a corresponding Ussing Chamber for studies of epithelial transport and the electrical properties of tissues. Measurements include transepithelial voltage, short circuit current and membrane resistance.
Differential voltage recordings are made with very high common mode rejection (CMR) providing accurate measurements free from the effects of common mode potential changes of a noisy environment.
Membrane Resistance Measurement Circuit using a low frequency 2 Hz bipolar signal to avoid polarization of the membrane (ideal for monolayers).
Three Clamp Speeds selection provide optimum recording conditions for a variety of applications, such as Fast mode (as fast as 10 µsec) for preparations with low access resistance (small tissues or monolayers) and Medium or Slow modes for stable, oscillation free clamping in larger tissues.
Operating modes include voltage clamp, current clamp, voltmeter, and resistance.
Independent Voltage and Current Commands.
Internal DC Command (Hold) control for both Voltage clamp and Current clamp modes.
The clamp can be operated by an external programmer, lab timer or computer — logic control of clamp mode and clamp command levels is possible as well as simultaneous mixing of external linear commands.
Watertight Headstage with Model Membrane